We provide a wide spectrum of wetlab technologies to tackle any scientific challenge
Cell culture
Custom-engineered cell lines and primary cells support a range of immunology applications, providing the foundation for reliable cell-based assays to assess cellular responses and drug effects, including reporter and potency assays.
Workflows include cell culture, cell line generation via nucleic acid or viral delivery, cell banking (MCB/WCB), mycoplasma testing, and cell viability measurements, ensuring high-quality, assay-ready models for immunology research and therapeutic development.
BSL2 viral transduction
Viral transduction under BSL-2 conditions provides high-efficiency delivery of genetic material into difficult-to-transfect host cells.
Especially suited for applications that require stable integration and sustained expression within the host genome, making it ideal for long-term studies or gene therapy where persistent gene expression is crucial.
Electroporation
Transfection techniques are efficient physical gene delivery methods, enabling transfection of various cell types. Whereas chemical transfection is typically used for transient gene expression, electroporation offers superior efficiency and minimal cytotoxicity, making it ideal for both transient and stable gene expression.
Its non-viral, high-throughput nature makes it invaluable for applications like CRISPR/Cas9 gene editing, RNA transfection, and cell engineering.
Flow cytometry
FCM is a powerful technique for multiparametric cell analysis, enabling simultaneous evaluation of multiple cellular (bio) markers.
This capability makes it an invaluable tool for immunophenotyping and detailed cell characterization, the design of functional assays and ensuring compliance with GMP standards in cell and gene therapy applications.
ELISA
ELISA is a reliable and widely adopted immunoassay technique used to detect and quantify proteins with high efficiency and sensitivity, making it an indispensable tool across various fields.
The technique is particularly valuable in both discovery phases (e.g., identifying new biomarkers) and in diagnostics (e.g., validating biomarkers or quantifying proteins in clinical samples).
Real-time PCR (RT-qPCR)
Quantitative PCR (qPCR) is a powerful technique for rapid and precise nucleic acid detection and quantification. It plays a key role in gene expression analysis, viral load measurement, genotyping and biomarker validation.
Custom PCR assay development, from design to optimization, provides reliable solutions for both manufacturing and preclinical research.
(Auto-) MACS primary cell isolation
Primary cells are essential for gene editing and functional studies, providing precise models for disease mechanism research and therapeutic strategy evaluation. The autoMACS is a powerful tool for automated isolation of specific cell types from sources like PBMCs or cultured cells, using either positive or negative selection methods.
This enables rapid, pure, and gentle isolation, making it ideal for downstream applications such as flow cytometry, functional assays, and omics.
Meso Scale Discoveries (MSD)
Multi-array technology, used in systems like the Meso Scale Discovery (MSD) platform, detects multiple biomarkers in a single sample using multi-array plates with specialized probes, enabling faster, cost-effective analysis and comprehensive data across multiple biomarkers simultaneously.
It uses detection methods like Electrochemiluminescence (ECL) and ELISA, making it ideal for applications in biomarker discovery, disease diagnostics, and drug development.
Gas chromato-graphy
Gas chromatography is an analytical technique used to separate and analyse compounds that can be vaporized without decomposition.
This technique provides high sensitivity and accuracy, making it ideal for detecting trace levels of volatile substances and chemicals within a complex mixture and to determine their concentrations.
Liquid chromato-graphy
Liquid chromatography is a powerful technique used to separate, identify, and quantify components in a liquid mixture based on their interactions with a stationary phase and a mobile phase.
It can be coupled to a variety of detectors and is commonly applied in pharmaceutical and biochemical research for precise and efficient analysis of complex mixtures, including drugs, oligonucleotides, proteins, and metabolites.
Spectrophoto-metry
Multimode spectrophotometers (microplate readers) enable efficient high-throughput assays, combining speed, versatility, and sensitivity.
Supporting absorbance, fluorescence, and luminescence detection modes, they are ideal for applications such as reporter gene assays, enzyme kinetics, ELISA, and protein or nucleic acid quantification.
HR-MS
High-resolution mass spectrometry (HRMS) is an advanced analytical technique that accurately measures the mass of molecules with high precision. It allows researchers to determine molecular formulas, identify unknown substances, and analyse complex mixtures with high sensitivity and specificity.
HRMS is widely used in fields such as pharmaceutical and biochemical science, and proteomics for detailed molecular analysis.
